Transforming
Healthcare Through
Intelligent Innovation

Sentrelia builds AI-powered clinical tools and partners with health systems to navigate the rapidly evolving landscape of healthcare technology — from strategy to deployment.

512K+
Patient Records Analyzed
0.926
AUC-ROC (Triage Tool)
2
National Datasets Validated
0
Extra Data Entry Required

Two Ways We Create Impact

We build the tools clinicians need today and help health systems build the capabilities they need for tomorrow.

AI Product Development

We design, develop, and validate AI-powered clinical decision support tools — built on rigorous research, trained on real-world data, and integrated directly into the systems clinicians already use.

  • Clinical decision support at point of care
  • Native Epic / CDS Hooks / FHIR R4 integration
  • Validated on large national and institutional datasets
  • Designed to support — not replace — clinical judgment
See our products →

Healthcare AI Advisory

We partner with hospital leadership and clinical operations teams to develop AI strategies, evaluate vendor solutions, and build the internal infrastructure needed to adopt AI responsibly.

  • AI readiness assessments and roadmaps
  • Vendor evaluation and procurement guidance
  • AI governance, ethics, and safety frameworks
  • Staff education and change management support
Learn about advisory →

Clinically Validated. EHR-Ready.

Tools built from the ground up for real clinical environments — not retrofitted from general AI.

Sentrelia Triage

An AI-powered emergency department triage tool that predicts ICU admission and critical outcomes at the moment of patient arrival — embedded directly into Epic with zero additional data entry.

0.926
AUC-ROC
99.3%
Negative Predictive Value
512K+
Encounters Trained On
CDS Hooks
Epic Integration Standard
Learn More About Sentrelia Triage →
Live CDS Alert · Epic Hyperspace
Epic Hyperspace — Triage
Smith, Robert J Age 71 · M
ESI 3
HIGH RISK — 42% critical outcome

Chest pain · HR 112 · BP 88/60 · SpO₂ 93%

Shock Index ↑ Hypoxia
42%
Powered by Sentrelia · NHAMCS + MIMIC-IV validated
Coming Soon

Additional clinical AI tools in development — covering sepsis early warning, readmission prediction, and more.

Stay updated →

Your Partner in Navigating Healthcare AI

Adopting AI in healthcare is complex. Between vendor hype, regulatory uncertainty, and clinical workflow challenges, most health systems don't know where to start. Sentrelia brings the clinical, technical, and operational expertise to guide your organization through every stage.

Talk to Our Advisory Team →

AI Readiness Assessment

We evaluate your current data infrastructure, workflows, and organizational capacity to identify where AI will create the most value — and where you need to build first.

Vendor Evaluation

Independent, evidence-based evaluation of AI vendors using clinical validation standards, integration requirements, and total cost of ownership frameworks.

AI Governance & Safety

Develop policies, monitoring frameworks, and ethical guidelines to ensure AI systems perform safely, equitably, and in alignment with your values.

Education & Change Management

Clinician and staff training programs that build AI literacy, improve adoption rates, and ensure sustainable integration into daily workflows.

Built by Clinicians and Engineers Who Understand the Stakes

Sentrelia was founded on a simple belief: the most transformative advances in healthcare happen when clinical expertise and cutting-edge technology work in concert. We are a team of physicians, data scientists, and health system operators committed to making AI safe, practical, and impactful in real clinical settings.

Our work is grounded in peer-reviewed research and validated against the largest publicly available emergency department datasets in the United States. We don't ship tools that haven't been rigorously tested — because we understand what's at stake.

2
National Datasets
5+
Years of NHAMCS Data
100%
EHR-Native

Our Core Values

1

Clinical First

Every decision starts with the question: does this help the clinician and the patient?

2

Rigorous Evidence

We hold our work to the same standards as clinical research — peer review, external validation, and transparent reporting.

3

Responsible AI

We audit for bias, ensure equity across patient populations, and maintain human oversight in every tool we build.

4

Partnership Over Transactions

We build long-term relationships with health systems — showing up as a partner, not just a vendor.

The People Behind Sentrelia

A multidisciplinary team combining clinical medicine, machine learning, and healthcare operations.

JH

J. Avery Harrell, MD

Co-Founder · Physician, Developer & Entrepreneur

Physician and developer combining frontline clinical experience with deep expertise in AI, EHR integration, and clinical decision support systems.

AM

Ayed Mahmoud, MD

Co-Founder · Physician, Developer & Entrepreneur

Physician and developer with a passion for applying AI to solve high-stakes clinical problems and drive meaningful innovation in health systems.

Join Our Team

We're Growing

We're looking for clinicians, engineers, and health system operators passionate about transforming healthcare.

Get in touch →

Ready to Bring Intelligent
Innovation to Your Health System?

Whether you're exploring our triage tool, looking for an AI advisory partner, or interested in a research collaboration — we'd love to talk.

Pilot Our Triage Tool

Run a structured pilot in your ED with our full support.

Engage Our Advisors

Get expert guidance on your healthcare AI strategy.

Research Collaboration

Partner with us on clinical AI research and validation studies.